Our Services

Operating model and organisational design

Protagoras works across the operating model to improve organisational effectiveness, providing:

Case studies

Click on each of the areas below to read some examples of the work that we have done across each component of the operating model.

Clinical development and portfolio management

Protagoras’ expertise in clinical development and portfolio management supports top global pharma companies in building assets’ development strategy across the product lifecycle

Portfolio strategy

Protagoras has worked with companies to develop and optimise their portfolio strategy, including investments, divestments, prioritisation and termination of development

Product strategy

Protagoras has supported cross-functional product teams in building the clinical development strategy for assets in various indications and across the product lifecycle, to enable better decision-making earlier and mitigate risk.

Vendor management

Protagoras has worked with R&D functions to institute vendor management best practices, vendor management dashboards, and vendor selection processes to ensure effective partnership whilst controlling cost

Discovery & early development

Protagoras teams have worked with research, early development, and translational science functions of top 20 pharma companies to optimise their operating models and the pre-clinical / clinical interface

Protagoras brings considerable experience in product & portfolio development strategy and understand the challenges that life science companies face both internally and externally.

Many companies have considerable expertise with certain indications and focus further R&D efforts within these areas, leading to cannibalisation of their own market.

Product development is a cross-functional endeavour, however working in a matrix can lead to competition over resources, lack of clarity in responsibilities, and sub-optimal outcomes.

A company invests heavily in assets and does not want to see them fail. Decisions around portfolio prioritisation or ceasing development can be deferred through a lack of available information.

The cost of bringing a product to market, including the cost of failures is around $7bn, with development times ranging between 18-12 years, leading to extremely high risks and costs for development organisations.

Regulatory requirements have substantially increased over the last decade, with increasing demand for value based evidence, patient reported outcomes and higher demands for efficacy. 

The industry is not stagnant; new products regularly come to market, and short delays can result in the difference between a first to market and a radical re-evaluation of a  clinical trial when a new SoC emerges.

Evidence generation requirements have increased at the same time that products are becoming increasingly targeted to smaller patient populations to improve differation.

Contact Research Organisations are perhaps the largest direct cost of any pharma company. Yet companies lack the expertise to manage the vendor performance and optimise working partnerships to improve differation.


Protagoras supports Biotech companies throughout the readiness roadmap.

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